Neuroscience Sheds Light on Why People with Asperger’s Syndrome Might Lack Empathy PsychCentral Find you are always trying to ‘explain’ the behavior of your Asperger child or spouse? No matter how much we explain or teach or train the Aspie mind, certain neurological circuits don’t work as they do in the NT brain. The brain has a number of circuits that are all connected like Christmas lights. If one part doesn’t work right, then the rest of the circuits malfunction, too. GREAT article, by Dr. Kathy Marshack, shedding light on why people with Aspergers Syndrome lack empathy.